FIGURE 2.

Rostral migratory stream in the adult mouse brain. A) De novo neurons born in the subventricular zone (SVZ) of the lateral ventricle (LV) migrate to the olfactory bulb (OB) through rostral migratory stream (RMS). The RMS tract is connected to subependymal layer (SE), the central part of the OB. In the RMS, migrating the neuroblasts form chains and they are surrounded by glial tube. Within the RMS, parallel-running blood vessels provide additional scaffolds for migrating neuroblasts. B, C) Double immunofluorescence labeling of migrating neuroblasts (red, DCX labeling) and glial tube (green, GFAP labeling) in the RMS. B) shows parasagittal, and C) shows coronal section image. Reproduced under CC-BY license.¹⁰