TABLE 7. Seroprotection rates and geometric mean titers among children aged 14 months–17 years in the Philippines before and after a booster dose of inactivated Vero cell culture–derived Japanese encephalitis vaccine administered 11 months after the second dose of a 2-dose primary series.
| Measure | 0
days |
1
mo |
12
mos |
24
mos |
||||
|---|---|---|---|---|---|---|---|---|
|
Seroprotection rate*
|
No.
seroprotected
(n = 148)
|
(%)
|
No.
seroprotected
(n = 148)
|
(%)
|
No.
seroprotected
(n = 147)
|
(%)
|
No.
seroprotected
(n = 143)
|
(%)
|
| 139 |
(94) |
148 |
(100) |
147 |
(100) |
143 |
(100) |
|
| GMT |
GMT
|
(95% CI)
|
GMT
|
(95% CI)
|
GMT
|
(95% CI)
|
GMT
|
(95% CI)
|
| 53 | (45–64) | 2,067 | (1,671–2,556) | 428 | (335–546) | 350 | (279–440) | |
Source: Kadlecek V, Borja-Tabora CF, Eder-Lingelbach S, et al. Antibody persistence up to 3 years after primary immunization with inactivated Japanese encephalitis vaccine IXIARO in Philippine children and effect of a booster dose. Pediatr Infect Dis J 2018;37:e233–40.
Abbreviations: CI = confidence interval; GMT = geometric mean titer.
* Proportion with 50% plaque reduction neutralization test titer ≥10.