Table 1.

Comparison of aquation rates of trans-platinum complexes and pK_a of the corresponding diaqua complexes.^[a][a]

Compound	k1(s−1)	pKa1	pKa2
trans-Pt(OAc)2(py)2][b]	3.2 ± 0.3 × 10−7	3.87	6.70
trans-[Pt(OAc)2(NH3)2][b]	< 10−7	4.0[c]	7.08[c]
trans-[PtC12(NH3)2]	19 × 10−5	--	--
cis-[PtC12(NH3)2]	5.18 × 10−5	--	--
[PtC1(dien)]+	6.50 ± 0.13 × 10−5	--	--

Adapted from Ref. [28].

^[b]Aqueous solubility 15.0 and 21.0 mg/mL for the NH₃ and pyr compounds respectively.

^[c]Literature values from NMR studies 4.35 and 7.40 for pK_a1 and pK_a2, respectively [28].