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. 2019 Jul 15;11(13):4672–4687. doi: 10.18632/aging.102078

Table 2. The information of most significant SNPs associated with facial wrinkle traits.

Trait Chr Nsnp Top SNP Pos(bp) Nearest Gene1 Distance (bp)2 Alleles Effect P-value Var(%)
Wrinkle pixel ratio 7 13 rs80983858 34835986 GRM4 3255 G/A -0.015 1.80×10-10 21.80%
Wrinkle score 7 14 rs80983858 34835986 GRM4 3255 G/A -0.755 8.75×10-14 31.30%
Multi-trait 7 13 rs80983858 34835986 GRM4 3255 G/A -0.755 4.45×10-13

1Nearest gene = the gene on or nearest to the most significant SNP.

2Distance = the distance from the most significant SNP to the nearest gene; negative value indicates the SNP is on the upstream to the gene, positive value indicates the SNP is on the downstream region.