Table 2. The information of most significant SNPs associated with facial wrinkle traits.
Trait | Chr | Nsnp | Top SNP | Pos(bp) | Nearest Gene1 | Distance (bp)2 | Alleles | Effect | P-value | Var(%) |
Wrinkle pixel ratio | 7 | 13 | rs80983858 | 34835986 | GRM4 | 3255 | G/A | -0.015 | 1.80×10-10 | 21.80% |
Wrinkle score | 7 | 14 | rs80983858 | 34835986 | GRM4 | 3255 | G/A | -0.755 | 8.75×10-14 | 31.30% |
Multi-trait | 7 | 13 | rs80983858 | 34835986 | GRM4 | 3255 | G/A | -0.755 | 4.45×10-13 |
1Nearest gene = the gene on or nearest to the most significant SNP.
2Distance = the distance from the most significant SNP to the nearest gene; negative value indicates the SNP is on the upstream to the gene, positive value indicates the SNP is on the downstream region.