Table 1. Characteristics of the participants.
| Variables | Controls (n = 102) | SCH (n = 199) | P value | SCH (n = 199) | P value | |
| Without CAD (n = 51) | With CAD (n = 148) | |||||
| Age (years) | 63.8 ± 8.2 | 64.4 ± 10.9 | 0.644 | 62.7 ± 10.7 | 65.0 ± 11.0 | 0.202 |
| Male, n (%) | 54 (52.9) | 92 (46.2) | 0.270 | 21 (41.2) | 71 (48.0) | 0.401 |
| BMI (kg/m2) | 24.3 (23.4–25.4) | 25.0 (23.0–27.0) | 0.250 | 25.6 (23.0–28.4) | 24.8 (23.0–27.0) | 0.137 |
| Smoking, n (%) | 47 (46.1) | 83 (41.7) | 0.469 | 18 (35.3) | 65(43.9) | 0.281 |
| Hypertension, n (%) | 74 (72.5) | 127 (63.8) | 0.128 | 33 (64.7) | 94 (63.5) | 0.879 |
| Diabetes, n (%) | 25 (24.5) | 67 (33.7) | 0.103 | 21 (41.2) | 46 (31.1) | 0.188 |
| SBP, mmHg | 135.0 (125.0–145.0) | 132.0 (120.0–145.0) | 0.374 | 130.0 (120.0–150.0) | 135.0 (120.0–145.0) | 0.689 |
| DBP, mmHg | 80.0 (70.0–86.0) | 80.0 (70.0–85.0) | 0.874 | 78.0 (70.0–90.0) | 80.0 (71.3–95.0) | 0.251 |
| TC (mmol/L) | 4.07 (3.63–4.53) | 3.98 (3.41–4.94) | 0.582 | 3.74 (3.34–4.48) | 4.20 (3.47–4.98) | 0.098 |
| TG (mmol/L) | 1.23 (0.98–1.58) | 1.34 (0.99–1.94) | 0.100 | 1.41 (1.05–2.25) | 1.31 (0.99–1.86) | 0.525 |
| LDL-C (mmol/L) | 2.54 ± 0.79 | 2.74 ± 0.88 | 0.066 | 2.55 ± 0.87 | 2.80 ± 0.88 | 0.074 |
| HDL-C (mmol/L) | 1.13 ± 0.28 | 1.04 ± 0.24 | 0.002 | 1.09 ± 0.29 | 1.02 ± 0.22 | 0.058 |
| ApoA (nmol/L) | 150.0 (116.0–265.0) | 189.0 (113.0–331.0) | 0.341 | 132.0 (61.0–339.0) | 202.5 (124.5–325.0) | 0.037 |
| FBG (mg/dL) | 97.92 (90.36–109.44) | 96.12 (87.12–114.30) | 0.689 | 107.46 (95.94–126.36) | 113.76 (97.74–144.36) | 0.137 |
| ALT (U/L) | 24.4 (23.4–25.8) | 24.8 (22.6–27.6) | .0338 | 25.3 (23.7–27.4) | 24.5 (22.3–27.7) | 0.174 |
| AST (U/L) | 25.3 (23.9–26.9) | 23.2 (19.3–32.7) | 0.051 | 23.2 (19.3–32.6) | 23.4 (19.3–32.9) | 0.869 |
| Cr (μmol/L) | 77.32 (73.51–83.55) | 75.80 (65.90–87.70) | 0.223 | 77.26 (72.53–83.99) | 77.64 (72.53–85.66) | 0.235 |
| UA (μmol/L) | 341.73 ± 94.47 | 341.91 ± 97.57 | 0.732 | 339.24 ± 94.88 | 342.83 ± 98.78 | 0.821 |
| TSH (mIU/L) | 3.45 (3.03–3.71) | 4.30 (4.23–4.40) | < 0.001 | 4.25 (4.22–4.36) | 4.32 (4.24–4.41) | 0.038 |
| FT3 (pmol/L) | 4.32 ± 0.43 | 4.28 ± 0.47 | 0.685 | 4.36 ± 0.50 | 4.26 ± 0.46 | 0.190 |
| T3 (nmol/L) | 1.93 ± 0.23 | 1.94 ± 0.44 | 0.923 | 2.05 ± 0.46 | 1.90 ± 0.44 | 0.037 |
| FT4 (pmol/L) | 16.00 (13.40–19.60) | 15.10 (14.70–15.70) | 0.010 | 15.10 (14.80–15.70) | 15.10 (14.60–15.70) | 0.345 |
| T4 (nmol/L) | 126.15 ± 9.82 | 122.58 ± 10.31 | 0.653 | 123.86 ± 9.56 | 122.20 ± 11.50 | 0.356 |
| RBP4 (μg/mL) | 35.07 ± 10.44 | 54.84 ± 12.30 | < 0.001 | 42.58 ± 8.76 | 58.29 ± 13.86 | < 0.001 |
Data are mean ± standard deviation, median with interquartile range in parenthesis, or number with percentage in parenthesis.
CAD, coronary artery disease; SCH, subclinical hypothyroidism; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoA, Apolipoprotein A; FBG, fasting blood glucose; ALT, alanine aminotransferase; AST, aspartate aminotransferase; Cr, creatine; UA, uric acid; TSH, thyroid stimulating hormone; FT3, free triiodothyronine; T3, Triiodothyronine; FT4, free thyroxine; T4, thyroxine; RBP4, retinol-binding protein 4.