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NLRP3 inflammasome was upregulated by PM exposure. (A) mRNA level of NLRP3 after PM in HPF. (B) Western blot analysis of NLRP3 and IL-1β after PM in HPF. (C) mRNA level of NLRP3 in Ex527-PM co-treated HPF models. (D) mRNA levels of NLRP3 in PF429242-PM co-treated HPF models. (E) Western blot analysis of PIR, SREBP1, and NLRP3 in TPh A-PM co-treated HPF models.
