Table 3. Blood level changes in small and middle molecules during a hemodialysis session.
| High-flux HD | MCO HD | |||||
|---|---|---|---|---|---|---|
| Pre-HD | Post-HD | P-value | Pre-HD | Post-HD | P-value | |
| Lambda FLC, mg/L | 165.9 ± 67.3 | 168.3 ± 73.8 | 0.557 | 132.0 ± 39.1 | 83.7 ± 31.6 | <0.001 |
| Kappa FLC, mg/L | 199.8 ± 79.5 | 138.4 ± 47.8 | <0.001 | 167.7 ± 65.8 | 63.0 ± 30.3 | <0.001 |
| β2-microglobulin, mg/L | 28.6 ± 7.4 | 10.0 ± 3.9 | <0.001 | 28.4 ± 4.8 | 6.8 ± 2.9 | <0.001 |
| Vitamin B12, pg/mL | 1148.5 ± 297.2 | 1282.3 ± 330.8 | <0.001 | 1118.2 ± 314.9 | 1301.6 ± 304.5 | <0.001 |
| Urea nitrogen, mg/dL | 59.6 ± 14.6 | 12.8 ± 4.6 | <0.001 | 54.7 ± 16.0 | 12.2 ± 5.8 | <0.001 |
Data are presented as mean ± SD. P-values for difference between pre-HD and post-HD blood levels were calculated by paired samples t-test or Wilcoxon signed-rank test. MCO, medium cut-off; HD, hemodialysis; FLC, free light chain.