Table 5. Metabolite correlation network analysis.
Parameter | GWI | Controls | P value |
---|---|---|---|
Total possible, unique pairwise correlations* | 63,903 | 63,903 | -- |
Significantly correlated metabolite pairs (FDR < 0.05) | 902 | 589 | <0.0001 |
Positively correlated metabolite pairs (FDR < 0.05) | 835 | 541 | ns |
Negatively correlated metabolite pairs (FDR < 0.05) | 67 | 48 | ns |
*By Spearman non-parametric correlation analysis. For a matrix of 358 metabolites: N = ((358 x 358)- 358)/2 = 63,903.