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. 2019 Jul 22;11:6755–6764. doi: 10.2147/CMAR.S199027

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© 2019 Fan et al.

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TM4SF1-KO MDA-MB-231 cells displayed a reduced tumor burden in BALB/c nude mice.

Notes: (A) Representative images of breast tumors in control group, TM4SF1-/- group, and miR-206 group (N=6). (B) Average tumor weight of control group, TM4SF1-/- group, and miR-206 group (N=6). (C) Representative pictures of H&E staining and immunohistochemistry of TM4SF1 for breast tumors in the control group, TM4SF1-/- group and miR-206 group (N=6). (D) The miR-206 amount in the tumors of control group, TM4SF1-/- group and miR-206 group (N=6) was detected by real-time PCR. (E) Western blotting analysis of TM4SF1 expression in the tumors of the control group, TM4SF1-/- group, and miR-206 group (N=6). *P<0.05; **P<0.01.

Abbreviations: TM4SF1, transmembrane 4 L6 family member 1; miR-206, microRNA-206; -/-, TM4SF1-knockout MDA-MB-231 cells.