Table 1.

Screening, assessment, and dependent study measures.

Measures	Individual tests
Genetic markers	SNCA (α-Synuclein), rs356219
	MAPT H1/H2 haplotypes (microtubule-associated tau), rs1800547
	APOE ɛ2/ɛ3/ɛ4 alleles (Apolipoprotein E), rs429358 and rs7412
Screening	Unified Parkinson Disease Rating Scale Motor Section III
Behavioral measures	Montreal Cognitive Assessment
	Beck Depression Inventory II
	Edinburgh Handedness Inventory
	Beck Anxiety Inventory
	The Parkinson Disease Sleep Scale
	The Parkinson Disease Questionnaire
	Neuropsychiatric Inventory of Psychopathology in Dementia
	Adelaide Activities Profile
Neuropsychological assessment	American New Adult Reading Test
	Digit Span and Letter Number Sequencing
	Phonemic and Semantic
	Hopkins Verbal Learning Test-Revised
	Benton Visuospatial Memory-Test Revised
	Boston Naming Test
	Judgment of Line Orientation
	Visual Object and Space Perception
	Visual Form Discrimination
	Stroop Color and Word Test
	Delis Kaplan Executive Function Scale Trails 1-5
	Delis Kaplan Executive Function Scale Tower Test
	Computerized Version of the Wisconsin Card Sorting Test
	Finger tapping
	Grooved pegboard
Neuroimaging	Cortical thickness; Voxel-based morphometry
	resting-state fMRI; Diffusion Tensor Imaging
	Task-activated fMRI imaging paradigm—object memory (encoding, immediate and delayed memory recall)