TABLE 2.
Agreement of micro- and macroalbuminuria defined by 24-hour albumin:creatinine ratio and urinary albumin concentration with that defined by 24-hour urinary albumin excretion, International Study of Macronutrients and Blood Pressure, 1996–2002
| Albumin measure and outpoints | Albuminuria category | Urinary albumin excretion |
κ | |||||
|---|---|---|---|---|---|---|---|---|
| Normal (<30 mg) |
Microalbuminuria (30–299 mg) |
Macroalbuminuria (≥300 mg) |
||||||
| No. | % | No. | % | No. | % | |||
| ACR*—INTERMAP* (table 1) | Normal | 4,424 | 99.7 | 9 | 4.4 | 0 | 0.0 | 0.935 |
| Microalbuminuria | 13 | 0.3 | 189 | 92.6 | 2 | 4.4 | ||
| Macroalbuminuria | 0 | 0.0 | 6 | 2.9 | 35 | 94.6 | ||
| Albumin concentration—INTERMAP (table 1) | Normal | 4,413 | 99.5 | 23 | 11.1 | 0 | 0.0 | 0.872 |
| Microalbuminuria | 24 | 0.5 | 174 | 85.3 | 5 | 13.5 | ||
| Macroalbuminuria | 0 | 0.0 | 7 | 3.4 | 32 | 86.5 | ||
| ACR—Warram et al. (20): men, 17–249 mg/g; women, 25–354 mg/g | Normal | 4,410 | 99.4 | 7 | 3.4 | 0 | 0.0 | 0.908 |
| Microalbuminuria | 27 | 0.6 | 194 | 95.1 | 7 | 18.9 | ||
| Macroalbuminuria | 0 | 0.0 | 3 | 1.5 | 30 | 81.1 | ||
| ACR—American Diabetes Association (13): 30–299 mg/g | Normal | 4,427 | 99.8 | 40 | 19.6 | 0 | 0.0 | 0.857 |
| Microalbuminuria | 10 | 0.2 | 161 | 78.9 | 9 | 24.3 | ||
| Macroalbuminuria | 0 | 0.0 | 3 | 1.5 | 28 | 75.7 | ||
| Albumin concentration—Bakker (19): 16–159 mg/liter | Normal | 4,406 | 99.3 | 22 | 10.8 | 0.0 | 0.855 | |
| Microalbuminuria | 32 | 0.7 | 173 | 84.8 | 6 | 16.2 | ||
| Macroalbuminuria | 0 | 0.0 | 9 | 4.4 | 31 | 83.8 | ||
*
ACR, albumin:creatinine ratio; INTERMAP, International Study of Macronutrients and Blood Pressure.