Table 3.
Serum lipids, uric acid, fibrinogen, and HbA1c in Japan and Hawaii, INTERLIPID 1997–1998, by gender and age
| 40–49 years |
50–59 years |
40–59 years |
|||||||
| 4 samples in Japan (287) Mean (s.d.) | Hawaii (47) Mean (s.d.) | 4 samples in Japan (285) Mean (s.d.) | Hawaii (53) Mean (s.d.) | 4 samples in Japan (572) Mean (s.d.) | Hawaii (100) Mean (s.d.) | ||||
| Men | |||||||||
| Serum total cholesterol (mg/dl) | 200.1 (28.6) | 206.0 (30.5) | P=0.191 | 198.5 (29.0) | 213.1 (27.4) | P<0.001 | 199.3 (28.8) | 209.8 (29.0) | P<0.001 |
| HDL-cholesterol (mg/dl) | 53.6 (l3.l) | 49.1 (10.6) | P=0.025 | 53.7 (14.2) | 51.2 (9.9) | P=0.111 | 53.7 (l3.7) | 50.2 (10.2) | P=0.003 |
| LDL-cholesterol (mg/dl) | 122.0 (28.3) | 130.9 (28.9) | P=0.047 | 119.0 (28.7) | 136.9 (27.5) | P<0.001 | 120.5 (28.5) | 134.1 (28.2) | P<0.001 |
| HDL-cholesterol/LDL-cholesterol | 0.471 (0.198) | 0.390 (0.110) | P<0.001 | 0.486 (0.216) | 0.389 (0.104) | P<0.001 | 0.479 (0.207) | 0.389 (0.106) | P<0.001 |
| Triglyceride (geometric mean, mg/dl) | 135.9 (1.8) | 194.8 (1.8) | P<0.001 | 133.6 (1.8) | 198.3 (1.9) | P<0.001 | 134.8 (1.8) | 196.6 (1.8) | P<0.001 |
| Lp (a) (geometric mean, mg/dl) | 8.5 (2.2) | 8.6 (2.7) | P=0.941 | 9.6 (2.3) | 8.7 (2.5) | P=0.410 | 9.0 (2.3) | 8.6 (2.6) | P=0.648 |
| γ-GTP (geometric mean, U/l) | 42.8 (2.2) | 35.8 (1.8) | P=0.077 | 43.6 (2.2) | 38.4 (1.7) | P=0.155 | 43.2 (2.2) | 37.2 (1.8) | P=0.024 |
| Uric acid (mg/dl) | 5.80 (1.18) | 5.99 (1.14) | P=0.316 | 5.83 (1.20) | 6.59 (1.17) | P<0.001 | 5.80 (1.20) | 6.30 (1.20) | P<0.001 |
| HbA1c (%) | 4.72 (0.50) | 4.92 (0.85) | P=0.132 | 4.82 (0.60) | 5.08 (0.73) | P=0.006 | 4.80 (0.60) | 5.00 (0.80) | P=0.006 |
| Fibrinogen (mg/dl) | 248.3 (71.6) | 288.9 (55.2) | P<0.001 | 259.0 (66.1) | 286.9 (60.4) | P=0.004 | 253.7 (69.0) | 287.8 (57.8) | P<0.001 |
| 40–49 years |
50–59 years |
40–59 years |
|||||||
| 4 samples in Japan (290) Mean (s.d.) | Hawaii (52) Mean (s.d.) | 4 samples in Japan (280) Mean (s.d.) | Hawaii (54) Mean (s.d.) | 4 samples in Japan (570) Mean (s.d.) | Hawaii (106) Mean (s.d.) | ||||
| Women | |||||||||
| Serum total cholesterol (mg/dl) | 194.7 (29.3) | 204.5 (30.6) | P=0.028 | 210.2 (30.6) | 218.2 (32.5) | P=0.082 | 202.3 (30.9) | 211.5 (32.2) | P=0.005 |
| HDL-cholesterol (mg/dl) | 61.1 (14.7) | 57.0 (10.8) | P=0.056 | 58.9 (13.7) | 62.3 (14.8) | P=0.109 | 60.0 (14.2) | 59.7 (13.2) | P=0.810 |
| LDL-cholesterol (mg/dl) | 117.2 (27.4) | 132.6 (30.3) | P<0.001 | 130.7 (30.9) | 141.3 (36.0) | P=0.048 | 123.8 (29.9) | 137.0 (33.5) | P<0.001 |
| HDL-cholesterol/LDL-cholesterol | 0.560 (0.251) | 0.460 (0.170) | P<0.001 | 0.485 (0.204) | 0.492 (0.255) | P=0.845 | 0.523 (0.232) | 0.476 (0.217) | P=0.052 |
| Triglyceride (geometric mean, mg/dl) | 89.2 (1.6) | 125.5 (1.7) | P<0.001 | 107.5 (1.6) | 151.2 (1.7) | P<0.001 | 97.8 (1.6) | 138.0 (1.7) | P<0.001 |
| Lp (a) (geometric mean, mg/dl) | 9.5 (2.3) | 12.2 (2.3) | P=0.051 | 11.7 (2.4) | 12.4 (2.5) | P=0.644 | 10.5 (2.4) | 12.3 (2.4) | P=0.087 |
| γ-GTP (geometric mean, U/l) | 16.9 (2.2) | 21.5 (1.8) | P=0.003 | 43.6 (2.2) | 38.4 (1.7) | P=0.002 | 43.2 (2.2) | 37.2 (1.8) | P<0.001 |
| Uric acid (mg/dl) | 3.95 (0.90) | 4.43 (0.95) | P<0.001 | 4.38 (0.85) | 4.85 (1.38) | P=0.019 | 4.20 (0.90) | 4.60 (1.20) | P<0.001 |
| HbA1c (%) | 4.52 (0.41) | 4.62 (0.44) | P=0.109 | 4.67 (0.46) | 4.87 (0.80) | P=0.078 | 4.60 (0.40) | 4.70 (0.70) | P=0.021 |
| Fibrinogen (mg/dl) | 250.5 (63.6) | 308.8 (63.0) | P<0.001 | 267.0 (66.1) | 312.3 (58.7) | P<0.001 | 258.6 (65.3) | 310.6 (60.6) | P<0.001 |