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. Author manuscript; available in PMC: 2020 Jun 10.
Published in final edited form as: J Control Release. 2019 Apr 9;303:42–54. doi: 10.1016/j.jconrel.2019.04.008

Figure 6. Histological assessment of local and distant tumors confirmed antitumor efficacy of the ADD-IT treatment protocol.

Figure 6.

A) On day 38, a subset of mice was euthanized and tumors were isolated for histology and IHC. Histological sections stained for H&E (upper row, whole tumor view) and (middle row, magnified view), CD8 (lower row, magnified view). Whole tumor sections and the magnified views enclosed by black boxes are shown. B) H&E stained histological sections of mice treated with either IT-ADD or IT and survived 101 days. Red arrowheads denote the inguinal lymph nodes. Scale bars correspond to 3 mm (whole tumor panels) and 100 µm (magnified panels).