Table 2.
The minimum, maximum, and median doses for all antimicrobial active ingredients for which Canadian defined daily doses for animals (DDDvetCAs) were assigned for poultry, by route of administration, and the number of products used to assign each DDDvetCA.
| Route of admin | Antimicrobial active ingredienta,b | Minimum dose | Maximum dose | Median dose | Ratio mean:median dosec | Number of products |
|---|---|---|---|---|---|---|
| Feed | Amprolium | 13.3 | 32.5 | 16.3 | 1.27 | 1 |
| Feed | Avilamycin | 2.9 | 2.9 | 2.9 | 1.00 | 1 |
| Feed | Bacitracin | 7.2 | 13.1 | 10.1 | 1.00 | 3 |
| Feed | Bambermycin (GP) | 0.3 | 0.3 | 0.3 | 1.15 | 1 |
| Feed | Chlortetracycline | 7.2 | 28.6 | 14.3 | 1.17 | 3 |
| Feed | Clopidol | 16.3 | 16.3 | 16.3 | 1.00 | 1 |
| Feed | Decoquinate | 3.9 | 3.9 | 3.9 | 1.00 | 1 |
| Feed | Diclazuril | 0.1 | 0.1 | 0.1 | 1.00 | 1 |
| Feed | Erythromycin | 28.6 | 28.6 | 28.6 | 1.00 | 1 |
| Feed | Halofuginone | 0.4 | 0.4 | 0.4 | 1.00 | 1 |
| Feed | Lasalocid | 13.0 | 13.7 | 13.3 | 1.00 | 2 |
| Feed | Maduramicin ammonium | 0.7 | 0.7 | 0.7 | 1.00 | 1 |
| Feed | Monensin | 13.0 | 13.0 | 13.0 | 1.00 | 3 |
| Feed | Narasin | 9.1 | 9.1 | 9.1 | 1.00 | 2 |
| Feed | Narasin_nicarbazin | 5.2 | 5.2 | 5.2 | 1.00 | 1 |
| Feed | Nicarbazin | 10.4 | 26.0 | 16.3 | 1.06 | 1 |
| Feed | Nicarbazin_narasin | 5.2 | 5.2 | 5.2 | 1.00 | 1 |
| Feed | Oxytetracycline | 7.2 | 28.6 | 14.3 | 1.17 | 8 |
| Feed | Benzylpenicillin (GP) | 0.3 | 0.3 | 0.3 | 1.05 | 2 |
| Feed | Procaine benzylpenicillin | 5.4 | 5.4 | 5.4 | 1.00 | 2 |
| Feed | Robenidine | 4.3 | 4.3 | 4.3 | 1.00 | 1 |
| Feed | Salinomycin | 7.8 | 7.8 | 7.8 | 1.00 | 5 |
| Feed | Semduramicin | 3.3 | 3.3 | 3.3 | 1.00 | 1 |
| Feed | Sulfadiazine_trimethoprim (ELDU) | 10.8 | 10.8 | 10.8 | 1.00 | 1 |
| Feed | Trimethoprim_sulfonamide (ELDU) | 2.2 | 2.2 | 2.2 | 1.00 | 1 |
| Feed | Tylosin | 26.0 | 26.0 | 26.0 | 1.00 | 4 |
| Feed | Virginiamycin | 2.9 | 2.9 | 2.9 | 1.00 | 4 |
| Feed | Zoalene (Dinitolmide) | 16.3 | 24.3 | 20.3 | 1.00 | 1 |
| Water | Amoxicillin | 12.0 | 12.0 | 12.0 | 1.00 | 2 |
| Water | Amprolium | 55.2 | 55.2 | 55.2 | 1.00 | 1 |
| Water | Apramycin (ELDU) | 23.0 | 23.0 | 23.0 | 1.00 | 1 |
| Water | Enrofloxacin (ELDU) | 5.8 | 5.8 | 5.8 | 1.00 | 1 |
| Water | Erythromycin | 13.3 | 26.6 | 19.9 | 1.00 | 1 |
| Water | Lincomycin | 3.7 | 3.7 | 3.7 | 1.00 | 2 |
| Water | Lincomycin_spectinomycin | 63.8 | 63.8 | 63.8 | 1.00 | 2 |
| Water | Neomycin | 8.1 | 55.8 | 20.4 | 1.07 | 8 |
| Water | Oxytetracycline | 5.6 | 40.9 | 18.6 | 1.01 | 11 |
| Water | Benzylpenicillin | 41.0 | 41.0 | 41.0 | 1.00 | 4 |
| Water | Benzylpenicillin (supp) | 3.8 | 3.8 | 3.8 | 1.00 | 3 |
| Water | Pyrimethamine_sulfaquinoxaline | 3.4 | 3.4 | 3.4 | 1.00 | 1 |
| Water | Spectinomycin_lincomycin | 127.7 | 127.7 | 127.7 | 1.00 | 2 |
| Water | Streptomycin (supp) | 19.6 | 19.6 | 19.6 | 1.00 | 3 |
| Water | Sulfamethazine | 143.8 | 335.4 | 230.0 | 1.03 | 4 |
| Water | Sulfaquinoxaline | 58.4 | 87.5 | 72.9 | 1.00 | 2 |
| Water | Sulfaquinoxaline_pyrimethamine | 11.2 | 11.2 | 11.2 | 1.00 | 1 |
| Water | Tetracycline | 11.1 | 40.9 | 20.4 | 1.05 | 13 |
| Water | Tylosin | 28.8 | 115.0 | 71.9 | 1.00 | 2 |
| Injectable | Ceftiofur (ELDU) (YA) | 2.6 | 2.6 | 2.6 | 1.00 | 1 |
| Injectable | Gentamicin (YA) | 4.8 | 16.8 | 10.8 | 1.00 | 1 |
| Injectable | Lincomycin_spectinomycin (ELDU) (YA) | 6.0 | 6.0 | 6.0 | 1.00 | 1 |
| Injectable | Spectinomycin_lincomycin (ELDU) (YA) | 12.0 | 12.0 | 12.0 | 1.00 | 1 |
ELDU, based on known extra-label drug use doses in circumstances where an antimicrobial is not licensed for use in this species, yet surveillance data has documented the use of this antimicrobial; GP, based on growth promotion doses as no treatment/prevention doses exist; YA, based on doses indicated for young animals; supp, based on doses from multiple ingredient products with low doses of antimicrobials.
Antimicrobial active ingredients written as: Active ingredient 1_active ingredient 2 = DDDvetCA for active ingredient 1 when used in combination with active ingredient 2.
Ratio mean:median dose = DDDvetCA/median dose.