TABLE 3.
Methylation status identified candidate sites of SH2B1 in five ASD-discordant MZ twins by pyrosequencing.
| Samples | Methylation status | |||
| Chr.16:28856729 | Chr.16:cg28856735 | Chr.16:cg28856743 | Mean | |
| TP1_1 | 0.6119 | 0.7808 | 0.7109 | 0.7012 |
| TP1_2 | 0.6174 | 0.7890 | 0.7609 | 0.7224 |
| |Δβ| | 0.0055 | 0.0082 | 0.0500 | 0.0212 |
| TP2_1 | 0.6311 | 0.8166 | 0.7564 | 0.7347 |
| TP2_2 | 0.7510 | 0.8455 | 1.0000 | 0.8655 |
| |Δβ| | 0.1199* | 0.0289 | 0.2436* | 0.1308* |
| TP3_1 | 0.4491 | 0.5842 | 0.5724 | 0.5352 |
| TP3_2 | 0.4262 | 0.6019 | 0.5835 | 0.5372 |
| |Δβ| | 0.0229 | 0.0177 | 0.0111 | 0.0020 |
| TP4_1 | 0.4938 | 0.6558 | 0.6268 | 0.5921 |
| TP4_2 | 0.4953 | 0.6667 | 0.6533 | 0.6051 |
| |Δβ| | 0.0015 | 0.0109 | 0.0265 | 0.0130 |
| TP5_1 | 0.7204 | 0.8376 | 1.0000 | 0.8527 |
| TP5_2 | 0.6308 | 0.7849 | 0.7734 | 0.7297 |
| |Δβ| | 0.0896 | 0.0527 | 0.2266* | 0.1230* |
TP, twin pair (_1, case and _2, control); |Δβ|, methylation difference; cutoff parameters, |Δβ| ≥ 0.1; *significant.