Table 3.
Mean KS, mean AT, median IS, median DS, mean VS in patients with PD (n = 61) and controls (n = 93) enrolled the second experiment
| Parameter | PD Off | PD On | P Value* | Controls | P Value** |
|---|---|---|---|---|---|
| Mean (95% CI) KS, taps | 49.11 (46.5–51.6) | 55.07 (52.1–57.9) | <0.001 | 60.3 (57.6–63.0) | <0.001 |
| Mean (95% CI) AT, msec | 122.5 (114.1–131) | 110.4 (102.9–118) | <0.001 | 112.1 (101.8–122.3) | 0.0008 |
| Median (IQR) IS, msec2 | 67494 (11275–340854) | 167786 (33318–609816) | 0.0397 | 6758 (4030–16664) | <0.001 |
| Median (IQR) DS, points | 1.044 (1.018–1.136) | 1.097 (1.026–1.205) | 0.0003 | 1.044 (1.013–1.110) | 0.7636 |
| Mean (95% CI) VS, cm/sec | 24.25 (22.99–25.5) | 27.29 (25.77–28.81) | <0.001 | 30.04 (28.31–31.76) | <0.001 |
*P values for the differentiation between on and off medication; **P values for the differentiation between off state and controls.
CI, confidence interval; IQR, interquartile range; PD, Parkinson's disease; KS, kinesia score; AT, akinesia time; IS, incoordination score; DS, dysmetria score; VS, velocity score.