Table 1.

Occurrence of apical cell protrusions and associated nuclear shape changes.

Cell and Condition	% cells with apical protrusions
MCF_ctrl	0%
MCF_noc	17% ± 6% *
MB_231_ctrl	9% ± 5%
MB_231_noc	55% ± 7% ##
MB_231_bleb	0%
MB_231_bleb_noc	15% ± 6%
MB_231_tryp 30 sec	11% ± 5%
MB_231_CytoD	17% ± 6%
MB_231_CytoD_noc	39% ± 8% ###
MB_231_GFPLA_noc	81% ± 5% ##

^###: p < 0.001;

^##: p < 0.01;

^*: p < 0.05.

All statistical comparisons (Chi-sq test with Bonferroni correction) are with respect to corresponding control for a given cell type). ctrl: control; noc: nocodazole; bleb: blebbistatin; tryp 30 sec: trypsinization for 30 s; CytoD: cytochalasin D; GFPLA: GFP-Lamin A. N > 30 cells for each condition. Values represent Mean ± SEM.