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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: J Dev Orig Health Dis. 2019 Jan 30;10(4):447–458. doi: 10.1017/S204017441800106X

Table 4.

Associations between Exposure Biomarkers (μg/L) and Birth Outcomes (n=56)

Birth-weight (g) a
Fenton z score b
Exposure c β (95% CI) p-value β (95% CI) p-value
Phthalates
    MnBP 39.25 (−78.24, 156.73) 0.51 0.12 (−0.13, 0.37) 0.34
    MBzP 11.02 (−75.68, 97.72) 0.80 0.06 (−0.12, 0.24) 0.52
    MCOMHP 11.57 (−74.68, 97.82) 0.79 0.06 (−0.12, 0.24) 0.51
    mCINP 92.52 (−22.70, 207.73) 0.11 0.21 −0.03, 0.46) 0.08
    MCPP 78.48 (2.95, 154.01) 0.04 0.19 (0.02, 0.35) 0.02
    meCPP 22.62 (−88.83, 134.08) 0.69 0.05 (−0.19, 0.29) 0.68
    MEHHP −3.38 (−119.37, 112.61) 0.96 −0.02 (−0.27, 0.23) 0.86
    MEHP 66.05 (−70.10, 202.19) 0.33 0.04 (−0.25, 0.34) 0.76
    MEOHP 6.30 (−108.48, 121.07) 0.91 −0.01 (−0.25, 0.24) 0.95
    MEP 3.80 (−72.02, 79.62) 0.92 0.02 (−0.14, 0.18) 0.82
    MiBP 31.42 (−65.96, 128.80) 0.52 0.04 (−0.17, 0.25) 0.69
    ΣDEHP d 17.77 (−106.54, 142.08) 0.78 0.02 (−0.25, 0.28) 0.91
    ΣDBP e 38.37 (−81.32, 158.07) 0.52 0.10 (−0.15, 0.36) 0.43
Phenols
    2,4-DCP −52.80 (−159.59, 53.99) 0.32 −0.10 (−0.32, 0.14) 0.44
    2,5-DCP 7.26 (−65.24, 79.75) 0.84 0.01 (−0.15, 0.16) 0.93
    BP-3 15.11 (−38.41, 68.64) 0.57 0.02 (−0.10, 0.13) 0.75
    BPA 13.18 (−88.64, 115.00) 0.80 0.01 (−0.21, 0.23) 0.94
    BPF 54.14 (−47.73, 156.00) 0.29 0.02 (−0.20, 0.23) 0.87
    BPS −150.42 (−294.85, −6.00) 0.04 −0.31 (−0.62, 0.002) 0.05
    BuPB −62.66 (−142.67,17.35) 0.12 −0.12 (−0.29, 0.05) 0.16
    EtPB 12.29 (−34.25, 58.83) 0.60 0.01 (−0.09, 0.10) 0.91
    MePB −31.87 (−90.54, 26.80) 0.28 −0.05 (−0.17, 0.07) 0.43
    PrPB −16.60 (−64.77, 31.56) 0.49 −0.03 (−0.13, 0.07) 0.51
    TCS −4.01 (−60.50, 52.48) 0.89 0.04 (−0.06, 0.16) 0.39
Metals f
    As 9.03 (−92.34, 110.39) 0.86 −0.002 (−0.22, 0.21) 0.98
    Ba 26.31 (−81.92, 134.54) 0.63 −0.08 (−0.16, 0.31) 0.52
    Cd 45.91 (−111.43, 203.26) 0.56 −0.07 (−0.38, 0.24) 0.65
    Cr 80.83 (−131.60, 293.26) 0.76 0.10 (−0.36, 0.55) 0.67
    Cu 20.83 (−146.22, 187.89) 0.80 −0.05 (−0.40, 0.30) 0.79
    Hg −46.59 (−165.60,72.43) 0.44 −0.08 (−0.34, 0.17) 0.51
    Mn −36.68 (−231.23, 157.87) 0.71 −0.18 (−0.59, 0.23) 0.39
    Mo 65.84 (−82.23, 213.92) 0.38 0.17 (−0.15, 0.48) 0.29
    Ni 72.87 (−90.92, 236.65) 0.38 0.10 (−0.25, 0.45) 0.58
    Pb 13.46 (−107.64, 134.57) 0.82 −0.07 (−0.31, 0.18) 0.60
    Se −29.09 (−254.83, 196.65) 0.80 0.01 (−0.46, 0.49) 0.96
    Sn −25.45 (−140.31, 89.42) 0.67 −0.07 (−0.31, 0.17) 0.55
    Tl 4.42 (−139.64, 148.48) 0.95 0.00 (−0.31, 0.30) 0.99
    Zn 36.69 (−94.83, 168.21) 0.58 0.08 (−0.20, 0.36) 0.55
Σ scores
    Phthalates 9.46 (−3.71, 22.63) 0.16 0.01 (−0.01, 0.04) 0.33
    Phenols 0.48 (−18.07, 19.04) 0.96 −0.01 (−0.04, 0.03) 0.82
    Metals f 4.13 (−4.81, 19.11) 0.24 0.01 (−0.02, 0.03) 0.67
    Total f 0.82 (−2.45, 7.56) 0.31 0.00 (−0.01, 0.01) 0.62
a

Multiple linear regression models were run for each toxicant/element adjusting for specific gravity, gestational age, and gender

b

Multiple linear regression models were run for each toxicant/element adjusting for Specific gravity

c

Natural log transformation

d

ΣDEHP includes metabolites: MeCPP, MeHHP, MEHP & MEOHP

e

ΣDBP includes metabolites: MnBP & MiBP

f

n=55