Table 2.
Pregnancy and delivery risk factors associated with infant hypoglycemia among 4066* infants at-risk for NH
| Pregnancy and Delivery Characteristics | Hypoglycemia ORADJ (95% CI)1 | IV Dextrose ORADJ (95% CI)1 |
|---|---|---|
| Gestational Diabetes | 1.7 (1.4–2.1) | 1.2 (0.8–1.8) |
| Preeclampsia | 0.9 (0.6–1.4) | 1.6 (0.8–3.0) |
| Gestational Age (term as ref) | ||
| Preterm | 2.4 (2.0–2.9) | 2.4 (1.7–3.4) |
| Post-Date | 1.1(0.9–1.4) | 0.6 (0.3–1.2) |
| Size for Gestational Age (appropriate for gestational age as ref) | ||
| Small for Gestational Age, SGA | 2.1 (1.7–2.5) | 2.6 (1.8–3.8) |
| Large for Gestational Age, LGA | 2.0 (1.7–2.5) | 2.7 (1.9–3.9) |
| Delivery BMI, Maternal (Normal (18.5 < 25) as ref) | ||
| Overweight (25< 30) | 1.0 (0.8–1.2) | 0.8 (0.4–1.3) |
| Obese, Class I (30 < 35) | 1.1 (0.9–1.3) | 1.3 (0.8–2.2) |
| Obese, Class II (35< 40) | 1.2 (0.9–1.5) | 1.4 (0.8–2.5) |
| Obese, Class III and above (≥40) | 1.3 (1.0–1.8) | 2.2 (1.2–3.9) |
| Delivery Method, C-section (vaginal as ref) | 1.1 (0.9–1.2) | 1.4 (1.1–1.9) |
1
Estimates are based on multiple logistic regression models for NH and NH requiring IV dextrose. Models include all maternal risk factors identified from univariate analysis as significant risk factors for infant hypoglycemia and/or IV dextrose administration.
*
Due to missing data for 536 infants, the total analytic sample for this analysis is 4066.