. Author manuscript; available in PMC: 2020 Jan 1.

Published in final edited form as: Clin Nutr. 2019 Jan 26;39(1):204–214. doi: 10.1016/j.clnu.2019.01.016

Table 3:

Biomarker correlation coefficients in primigravidae and nulliparae

	Ferritin*	Adjusted ferritin*	sTfR*	ZnPP*	Hepcidin*	sTfR/log₁₀Fer*	Hb	RDW	MCHC	MCV	Adjusted BIS
Primigravidae at ANC1
Ferritin*	1
sTfR*	−0.052	− 0.196	1
ZnPP*	0.018	− 0.069	0.502	1
Hepcidin*	0.628	0.633	− 0.302	− 0.226	1
sTfR/log₁₀Fer*	− 0.530	− 0.564	0.871	0.442	− 0.560	1
Hb	− 0.259	− 0.130	− 0.403	− 0.606	0.127	− 0.230	1
RDW	− 0.015	− 0.060	0.343	0.481	− 0.185	0.306	− 0.379	1
MCHC	− 0.003	0.054	− 0.239	− 0.129	0.103	− 0.211	0.343	− 0.393	1
MCV	0.247	0.277	0.139	− 0.028	0.016	− 0.003	− 0.154	− 0.078	− 0.336	1
Adjusted BIS	0.863	0.924	− 0.488	− 0.256	0.675	− 0.832	0.042	− 0.187	0.142	0.144	1
CRP*	0.372	0.096	0.208	0.307	0.125	0.005	− 0.490	0.156	− 0.199	0.137	0.003
Nulliparae at FIN
Ferritin*	1
sTfR*	− 0.303	− 0.338	1
ZnPP*	− 0.388	− 0.429	0.632	1
Hepcidin*	0.656	0.629	− 0.348	− 0.420	1
sTfR/log₁₀Fer*	− 0.679	− 0.688	0.901	0.673	− 0.561	1
Hb	0.340	0.364	− 0.483	− 0.652	0.348	− 0.538	1
RDW	− 0.318	−0.335	0.431	0.578	− 0.333	0.482	− 0.474	1
MCHC	0.331	0.353	− 0.336	− 0.455	0.295	− 0.417	0.594	− 0.267	1
MCV	0.269	0.287	− 0.306	− 0.417	0.212	− 0.364	0.398	− 0.577	0.083	1
Adjusted BIS	0.892	0.937	− 0.644	− 0.543	0.640	− 0.892	0.474	− 0.432	0.411	0.347	1
CRP*	0.183	− 0.099	0.103	0.123	0.129	− 0.001	− 0.068	0.042	− 0.063	− 0.053	− 0.119

sTfR: serum transferrin receptor sTfR/log₁₀Fer: sTfR/log₁₀ferritin ratio; ZnPP : whole blood zinc protoporphyrin; Hb:hemoglobin; RDW: Red cell distribution width; CRP : C-reactive protein; MCV= mean corpuscular volume; MCHC: mean corpuscular hemoglobin concentration; BIS: body iron stores.

Asterisk: log₁₀ transformed. Adjusted ferritin based on internal regression correction allowing for inflammation based on CRP.

Cell sample sizes for pregnant women vary from 282 to 314 and for non-pregnant women from 882 to 897. P values for individual cell correlations are shown in Table S1 supplementary file. P values for a comparison of the relationships between biomarkers in pregnant and non-pregnant women in Table 2 are shown in Table S2 supplementary file.