Fig. 7.

High densities of atherosclerosis-associated DMRs span the HOXC and HOXA gene clusters. (A) Part of the HOXC gene cluster (chr12:54,352,494-54,384,543). Gray highlighting in BS-seq athero aorta track, athero hypermeth DMRs that overlap regions of low methylation in monocytes. (B) Most of the HOXA gene cluster (chr7:27,131,681-27,209,593). Genes in purple font, these genes had their athero hypermeth or hypometh status previously determined at a few CpGs by Illumina microarray assays alone and with pyrosequencing assays on 15 matched pairs of atherosclerotic and control aorta with results consistent with those shown [2].