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. 2019 Jul 22;12:181–194. doi: 10.2147/JIR.S213594

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© 2019 Eliasse et al.

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CD4⁺ T cells stimulated with DC_ASW exhibit a reduced ability to produce IFN-γ. (A,B) Amount of IFN-γ (A) or TNF (B) measured in the supernatant of CD4⁺ T cell co-cultures in indicated conditions. (C-D) Percentage of IL-17⁺ CD4⁺ T cells (C) and IFN-γ⁺ CD4⁺ T cells (D) following restimulation with PMA and ionomycine after 5 days of coculture. Each point represents an experiment (n=14 donors, 2 independent experiments). Bars indicate the mean ± SD. One-way ANOVA (Dunnett’s multiple comparison test). *p<0.05;***p<0.001; ****p<0.0001; ns, not significant.

Abbreviations: ASW, Avène thermal spring water; DC, dendritic cell; CTW, control water; DEX, dexamethasone.