Table S1.
Example of a random choice task. Twelve random choice tasks without an “opt-out” or “no-treatment” option were included in the discrete choice experiment.
DMARD characteristic | Medicine 1 | Medicine 2 |
---|---|---|
Route of administration | Oral (tablets/capsules) | Subcutaneous (injection in the upper leg or abdomen) |
Frequency of administration | Weekly | Monthly |
Onset of action | Six weeks | 12 weeks |
Risk of cancer (eg, skin cancer with favorable prognostic factors) | No risk | 1 of 1,000 patients (0.1%) |
Risk of liver injury (eg, higher levels of liver damage markers) | 1 of 1,000 patients (0.1%) | No risk |
Risk of serious infections (eg, hospital admissions/discontinuation of anti-rheumatic drugs) | No risk | 1 of 1,000 patients (0.1%) |
Chance of efficacy | 80% | 60% |
Preference for Medicine 1 or Medicine 2 | □ | □ |
Abbreviation: DMARD, disease-modifying antirheumatic drug.