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. 2019 Jul 27;18:42. doi: 10.1186/s12937-019-0467-x

Table 3.

Multivariable linear regression analysis of independent variables affecting serum testosterone levels (nmol/L), n = 256

Model 1 a Model 2 b Model 3 c
β (95% CI) P β (95% CI) P β (95% CI) P
Age (years) 0.01 (−0.02, 0.03) 0.63 0.00 (− 0.02, 0.03) 0.78 0.01 (− 0.03, 0.04) 0.78
BMI (kg/m2) − 0.11 (− 0.18, − 0.05) <  0.001 − 0.11 (− 0.18, − 0.05) <  0.001 − 0.11 (− 0.19, − 0.04) 0.004
FBG (mmol/L) −0.15 (− 0.32, 0.01) 0.07 −0.09 (− 0.26, 0.08) 0.30 −0.21 (− 0.53, 0.11) 0.20
TG (mmol/L) −0.49 (− 0.68, − 0.30) <  0.001 −0.42 (− 0.61, − 0.22) <  0.001 −0.51 (− 0.77, − 0.24) <  0.001
TC (mmol/L) −0.12 (− 0.34, 0.09) 0.25 −0.07 (− 0.28, 0.14) 0.50 −0.14 (− 0.42, 0.13) 0.31
HDL-C (mmol/L) 0.69 (0.00, 1.37) 0.05 0.36 (−0.34, 1.06) 0.31 0.53 (−0.29, 1.35) 0.20
LDL-C (mmol/L) 0.04 (−0.21, 0.28) 0.77 0.09 (−0.15, 0.32) 0.48 −0.02 (− 0.34, 0.31) 0.93
TC/HDL-C ratio −0.36 (− 0.59, − 0.13) 0.002 −0.23 (− 0.48, 0.01) 0.06 −0.42 (− 0.75, − 0.08) 0.014
BUN (mmol/L) −0.08 (− 0.25, 0.10) 0.38 −0.07 (− 0.24, 0.10) 0.40 0.01(− 0.19, 0.21) 0.92
Creatinine (μmol/L) −0.03 (− 0.04, − 0.01) 0.015 −0.02 (− 0.04, 0.00) 0.049 −0.02 (− 0.04, 0.01) 0.13
eGFR (mL/min/1.73 m2)
 T3 Ref Ref Ref
 T2 −0.72(− 1.18, − 0.26) 0.002 − 0.62 (− 1.08, − 0.17) 0.007 −0.88 (− 1.43, − 0.33) 0.002
 T1 − 0.94 (− 1.44, − 0.44) 0.001 −0.81 (− 1.31, − 0.31) 0.002 −0.80 (− 1.40, − 0.20) 0.010

BMI body mass index, FBG fasting blood glucose, TG triglycerides, TC total cholesterol, HDL-C high density lipoprotein-cholesterol, LDL-C low density lipoprotein-cholesterol, TC/HDL-C total cholesterol-to-high density lipoprotein-cholesterol, BUN blood urea nitrogen, eGFR estimated glomerular filtration rate

a Model 1: adjusted for age

b Model 2: adjusted for age and BMI

c Model 3: adjusted for model 2 and for education level, marital status, family income, smoking, drinking alcohol, sleeping, physical activity, cardiovascular disease, hypertension, diabetes, and CRP levels