Table 1.
Numbering and comparison of PKA, LRRK2, and BRAF spine residues
| Motif and numbering | PKA | LRRK2 | BRAF |
| C-spine | |||
| CS8 | A70 | A1904 | A481 |
| CS7 | V57 | V1893 | V471 |
| ATP | ATP | ATP | |
| CS6 | L173 | L2001 | F583 |
| CS5 | I174 | L2002 | L584 |
| CS4 | L172 | V2000 | I582 |
| CS3 | M128 | L1955 | L537 |
| CS2 | L227 | L2062 | V645 |
| CS1 | M231 | I2066 | L649 |
| R-spine | |||
| RS4 | L106 | L1935 | F516 |
| RS3 | L95 | L1924 | L505 |
| RS2 | F185 | Y2018 | F595 |
| RS1 | Y164 | Y1992 | H574 |
| “Shell” | |||
| Sh3 | M118 | L1945 | I526 |
| Sh2 | M120 | M1947 | M528 |
| Sh1 | V104 | I1933 | L514 |
| Regulatory triad | |||
| RT3 | D185 | D2017 | D594 |
| RT2 | E91 | E1920 | E501 |
| RT1 | K72 | K1906 | K483 |
| Hydrophobic network | |||
| HN1 | L74 | F1908 | L485 |
Sh, shell residues.