FIG A4.
Proportion of parameter space controlled by radiotherapy (RT) alone, RT after surgical resection (SR), and RT before surgical resection (RS) for different values of (A) the lysis rate of tumor cells killed by RT (n) and (B) the T cell–cancer interactions constant (a; Equations 1 to 3). Radiation is delivered to a total dose of 50 Gy in 25 daily fractions at 2 Gy per day, 5 days per week. For all simulations, we set RT-induced antitumor immunity to q = 4.5 × 10−1 day−1 and tumors of 108 viable cancer cells pretreatment.