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. Author manuscript; available in PMC: 2019 Jul 28.
Published in final edited form as: Interv Cardiol Clin. 2016 Jun 21;5(3):307–320. doi: 10.1016/j.iccl.2016.02.007

Figure 7.

Figure 7

Enhanced drug delivery capabilities from stents coated with absorbable polymer and crystalline drug. (A) Histopathology at 30d identified coating as the ‘negative image’ of space occupying mass (arrows) between struts (S). (B) Drug release is complete within 45–60 days after stent implantation, yet tissue levels remain at near peak levels long after.(C,D) Computational modeling predicted drug (C) and receptor binding (D) distribution patterns around a strut pair that is fully coated (conformal) or where the bottom coating deployed 35, 100, or 400 µm into interstrut zones. Figures A–D reproduced with permission from(3).