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. 2019 Jul 27;20:349. doi: 10.1186/s12891-019-2729-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Relaxin disrupts the balance between MMPs and TIMP. a: Immunohistochemical staining of TIMP1, MMP1, MMP9, and MMP13 in the tendon wound areas in the 2nd and 4th postoperative weeks. (Scale bar = 200 μm). b: Relative expression of MMP1, MMP9, MMP13 and TIMP1 in tendon wound areas. MMP9 and MMP13 shows a significant difference in the 2nd and 4th postoperative weeks. *p < 0.001 compared with vehicle group