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. 2019 Jul 27;19:134. doi: 10.1186/s12871-019-0808-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Blockade of the PI3K/Akt/mTOR pathway reduced the anti-inflammatory activity of dexmedetomidine Western blot measurements of IL-6, IL-8 and TNF- α from cortical and hippocampal samples of rats in the DEX and DEX + LY294002 groups (mean ± SD, n = 5 per group, t test). *p < 0.05 vs DEX group