Fig. 2.
Kb-SIINFEKL presentation on 293Kb cell surface after IAV infection. SIINFEKL is inserted into the stalk region of neuraminidase (NA). Source protein (NA) and Kb-SIINFEKL levels were analyzed as in Subheading 3.3. (a) Time course showing Kb-SIINFEKL expression paralleled NA expression, indicating SIINFEKL generation from DRiPs. (b) At 8 hpi, in response to a treatment, expression levels of both NA and Kb-SIINFEKL were downregulated, while the ratio (peptide presentation efficiency) was unchanged