Fig. 2.

Effects of HC diet on hepatic mRNA and protein expression of representative coagulation factors. a-c Effect of HC diet on liver Tf, Cpb2 and Pai-1 mRNA levels in WT (+/+) and Ppara-null (−/−) mice. d-g Effect of HC diet on liver protein levels of tissue factor (TF), carboxypeptidase B2 (CPB2), and plasminogen activator inhibitor-1 (PAI-1) in WT (+/+) and Ppara-null (−/−) mice. Black bars indicate control groups (Con) and white bars indicate HC diet-fed groups (Cho). Values are mean ± SD (n = 6 for each group). Data were compared between two groups using two-way ANOVA. Significant differences are indicated by *p < 0.05 and **p < 0.01