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Effects of diet on mRNA expression and DNA-binding activity of PPARs. a Effect of HC diet on Pparα (a), Ppard (d) and Pparg (g), mRNA expression in WT (+/+) and Ppara-null (−/−) mice. b Effect of HC diet on the DNA-binding activity of PPARα, PPARδ, and PPARγ in WT (+/+) and Ppara-null (−/−) mice. Values are mean ± SD (n = 6 for each group). Black, striped and white bars indicate PPARα, PPARδ, and PPARγ, respectively. Con and Cho indicates control and HC diet-fed groups, respectively
