Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Cytotoxic effects of AZD2461after 24, 48, and 72 h post treatment analyzed by MTT assay on (A) DU145 and (B) PC-3 cell lines.*p < 0.05 significance compared to adjacent untreated control. All assays were done in triplicate. The data shows that in same concentrations, PC-3 cells are more sensitive to PARP inhibition by AZD2461 than DU145 cells, which express high levels of PTEN
