Table 1.

Demographic, symptom and hormone levels for children with anxiety disorders (ADs) and controls.

Demographics	Control	AD	p-values	Control Girls	AD Girls	p-values	Control Boys	AD Boys	p-values
Total; number (% female)	46 (50%)	52 (51%)	0.854	23 (100%)	27 (100%)		23 (0%)	25 (0%)
Age (years); mean (SD)	10.58 (1.29)	10.42 (1.33)	0.701	10.74 (1.32)	10.50 (1.23)	0.633	10.38 (1.30)	10.39 (1.43)	0.987
IQ (WASI); mean (SD)	119.52 (13.44)	117.42 (13.52)	0.377	119.00 (16.33)	116.12(12.81)	0.313	120.04(10.11)	118.72(14.33)	0.696
Physical development (Tanner); mean (SD)	3.93 (2.06)	4.04 (1.87)	0.14	4.20 (2.09)	4.65 (2.00)	0.095	3.36 (1.71)	3.67 (1.86)	0.607
Symptom measure scores
Anxiety (parent SCARED); mean (SD)	7.21 (8.83)	28.59 (12.71)	<0.001*	6.01 (6.13)	29.56(12.00)	<0.001*	6.10 (8.26)	27.78(13.15)	<0.001*
Anxiety (child SCARED); mean (SD)	13.41 (11.26)	25.93 (13.71)	<0.001*	12.44 (9.93)	31.20(13.73)	<0.001*	11.92 (9.23)	21.36(12.52)	0.005*
Depression (CDI); mean (SD)	28.68 (18.87)	38.52 (21.21)	<0.001*	27.18(18.96)	44.81(21.26)	<0.001*	27.52(17.73)	33.32(19.80)	0.010*
ADHD (CPRS-R); mean (SD)	45.67 (6.91)	61.06 (12.74)	<0.001*	46.05 (4.68)	65.40(14.24)	<0.001*	42.74 (2.68)	57.25 (9.34)	<0.001*
Endocrines Measures
Cortisol (Saliva); mean (SD)	0.100 (0.038)	0.102 (0.039)	0.894	0.095(0.042)	0.107(0.041)	0.738	0.104(0.033)	0.095(0.036)	0.505
Testosterone (Saliva); mean (SD)	24.113(9.322)	22.628(12.330)	0.216	28.538(8.449)	25.389(14.719)	0.155	18.883(7.659)	19.176(7.579)	0.469
Estradiol (Saliva); mean (SD)	0.778 (0.313)	0.648 (0.350)	0.037*	0.788(0.377)	0.650(0.415)	0.184	0.766(0.233)	0.645(0.261)	0.205

^*indicates two-tailed significance