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. Author manuscript; available in PMC: 2020 Aug 10.
Published in final edited form as: Neuroscience. 2019 Jul 2;413:252–263. doi: 10.1016/j.neuroscience.2019.06.028

Fig. 2.

Fig. 2

Intra-VTA mecamylamine attenuates cue-induced cocaine seeking. (A) Experimental timeline. (B) Cocaine self-administration training showing active vs inactive lever presses, based on experimental assignments for the cue-induced cocaine-seeking test. (C) VTA mecamylamine reduces active lever responding but not inactive lever pressing. (D) VTA scopolamine attenuates within-session responding on the active lever. Error bars indicate the standard error from the mean (SEM). * p < 0.001, (active lever for 0 vs. 10 μg mecamylamine and 0 vs. 30 μg mecamylamine, post-hoc with Bonferroni correction).