Table 4.
Risk of Biopsy Confirmed Benign Breast Disease (BBD) related to body size and dietary factors from infancy through adolescence in females from the Growing Up Today Study (7144 girls, 173 BBD cases), born 1980–1987. Body size factors were previously found [31] to be most strongly associated with BBD, while dietary factors were those found most important in Table 3 Multivariable Models.
| Categorical Exposures Model | ||||
|---|---|---|---|---|
| OR (p) | OR (p) | OR (p) | Ptrendb | |
| Maternal BBD | No | Yes | ||
| 1.00 (ref) | 1.84 (.0004) | |||
| Maternal BC | No | Yes | ||
| 1.00 (ref) | 2.20 (.0015) | |||
| Gestational Weight Gain | < 20 lbs | > 20 to 35 lbs | > 35 lbs | |
| 1.00 (ref) | 0.57 (.02) | 0.61 (.07) | 0.26 | |
| BMI at 10yr (kg/m2) | Bottom 25% | Middle 50% | Top 25% | |
| 1.00 (ref) | 0.81 (.36) | 0.62 (.10) | 0.078 | |
| Height at 10yr (in) | Bottom 25% | Middle 50% | Top 25% | |
| 1.00 (ref) | 4.31 (.001) | 3.64 (.01) | 0.01 | |
| Peak Height Velocity | Bottom 25% | Middle 50% | Top 25% | |
| 1.00 (ref) | 1.85 (.049) | 2.31 (.014) | 0.018 | |
| Animal (non-dairy) fata intake at 10yr (Energy-adjusted) | Bottom 25% | Middle 50% | Top 25% | |
| 1.00 (ref) | 1.28 (.46) | 2.27 (.016) | 0.007 | |
| Peanut Butter & Bags of Nuts at 14yr | Bottom 25% | Middle 50% | Top 25% | |
| 1.00 (ref) | 0.67 (.068) | 0.60 (.033) | 0.099 | |
a
At age 10yr, the major contributors to animal (non-dairy) fat intake were beef or lamb as a main dish, and pork, ribs, or ham as a main dish.
b
Tests for trend (Pt) were performed by using the median exposure value, within each category, as a continuous variable.