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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Biometrics. 2019 Mar 29;75(3):1000–1008. doi: 10.1111/biom.13031

TABLE 2.

Powers for detecting at least one AE at the nominal significance level of 0.05 based on 1,000 replicates.

n ρ r Bonf. (Fisher) Bonf. (Score) Perm. (Fisher) Perm. (Score) Proposed
Simulation settings mimicking Example One
100 0 0 0.034 0.091 0.200 0.201 0.211
0.3 0 0.036 0.094 0.189 0.178 0.190
0.6 0 0.032 0.072 0.183 0.190 0.190
0.9 0 0.035 0.076 0.183 0.181 0.190
0.3 0.15 0.029 0.077 0.186 0.188 0.193
0.6 0.3 0.029 0.070 0.177 0.179 0.180
0.9 0.45 0.028 0.072 0.161 0.147 0.152
200 0 0 0.161 0.229 0.384 0.378 0.379
0.3 0 0.159 0.221 0.372 0.363 0.358
0.6 0 0.140 0.217 0.372 0.359 0.361
0.9 0 0.151 0.198 0.344 0.340 0.337
0.3 0.15 0.147 0.219 0.374 0.366 0.364
0.6 0.3 0.151 0.215 0.364 0.353 0.350
0.9 0.45 0.159 0.221 0.360 0.354 0.356
Simulation settings mimicking Example Two
100 0 0 0.009 0.055 0.450 0.465 0.577
0.3 0 0.006 0.043 0.459 0.477 0.592
0.6 0 0.007 0.047 0.458 0.480 0.592
0.9 0 0.006 0.048 0.500 0.541 0.633
0.3 0.15 0.006 0.054 0.457 0.484 0.589
0.6 0.3 0.009 0.049 0.458 0.486 0.575
0.9 0.45 0.007 0.041 0.503 0.561 0.614
200 0 0 0.327 0.631 0.947 0.981 0.973
0.3 0 0.320 0.608 0.946 0.978 0.972
0.6 0 0.322 0.613 0.958 0.978 0.972
0.9 0 0.353 0.615 0.966 0.984 0.980
0.3 0.15 0.330 0.597 0.948 0.975 0.967
0.6 0.3 0.326 0.593 0.940 0.964 0.958
0.9 0.45 0.310 0.576 0.953 0.970 0.970