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. 2019 Jul 23;12:5967–5977. doi: 10.2147/OTT.S197456

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© 2019 Wang et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

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Effect of miR-27a on proliferation and radiosensitivity in ESCC cells.

Notes: (A) miR-27a inhibited ESCC cells proliferation. CCK-8 assays were performed to evaluate cell proliferation at 0–4 days after transfection of miR-NC or miR-27a mimics in Eca109 and Eca9706 cells (*P<0.05, **P<0.01). (B) miR-27a radiosensitized ESCC cell lines. ESCC cells were transfected with miR-NC or miR-27a mimics and then irradiated with 0, 2, 4, 6, 8 Gy. Clonogenic assays were performed and surviving fractions were fitted to the linear-quadratic equation (*P<0.05, **P<0.01).

Abbreviations: ESCC, esophageal squamous cell carcinoma; miR-NC, negative control miRNA.