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. 2019 Jul 23;12:5967–5977. doi: 10.2147/OTT.S197456

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© 2019 Wang et al.

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miR-27a enhanced radiosensitivity of ESCC in xenograft models.

Notes: (A) Tumor growth curves presented by tumor volume indicated that miR-27a inhibited ESCC xenografts growth after radiation (*P<0.05, **P<0.001). (B) Tumor images of different groups after radiation. (C and D) IHC staining was used to detect the expression of Hsp90, p-EGFR and cleaved PARP in the xenograft sections (scale bar =50 μm). *P<0.05, **P<0.001.

Abbreviations: ESCC, esophageal squamous cell carcinoma; NC, negative control; Hsp90, heat shock protein 90.