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. Author manuscript; available in PMC: 2019 Jul 29.
Published in final edited form as: Arch Toxicol. 2018 Mar 20;92(7):2259–2271. doi: 10.1007/s00204-018-2192-1

Fig 5.

Fig 5.

PMB had high affinity for DNA and inhibited electrophoretic migration of plasmid at higher concentrations. (A) 60 ng of pBlueScript II DNA incubated with PMB (12.5–500 μM) in a topoisomerase I buffer for 2 h at 37 °C. Samples were resolved by electrophoresis. (B) Chemical structure of PMB with potential DNA binding sites (including the Dab residues) highlighted.