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circNrxn2 Promoted WAT Browning and Increased M2 Macrophage Polarization by Activating the PPARγ Signaling Pathway
(A and B) PPARγ agonist (A) and antagonist (B) were injected in HFD mice adipose tissue combined with circNrxn2, miR-103, and FGF10 after circNrxn2, miR-103, or FGF10 treatment. The mRNA levels of PPARγ, UCP1, CD206, and IL-6 were detected. Data represented the mean ± SEM. ∗p < 0.05; ∗∗p < 0.01. n ≥ 3.
