Table 1.

Patients’ demographics and clinical findings

Item	Value
Total (n)	359
Female	9
Male	350
Age (yr)	41 [16-69]
Dose (mg)	1,500 [500-4,000]
Seizures	52 (14.5)
Seizure tramadol dose (mg)	2,700 [1,300-4,000]
No seizure tramadol dose (mg)	1,450 [500-3,250]
Serotonin toxicity	0 (0.0)
Gastrointestinal symptoms	192 (53.5)
Intensive care unit	7 (1.9)
Respiratory depression	73 (18.5)
Intubated/ventilated	11 (3.6)
Length of stay (hr)	28 [12-136]
Max heart rate (bpm)	100 [88-140]
Max systolic BP (mmHg)	135 [100-160]

Values are presented as median [range] or number (%).

Max, maximum; BP, blood pressure.