Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
TMZ and O6-BG dosing schedules according to Quinn et al.
| Dosage regime | Dosing schedule of TMZ | Dosing schedule of O6- BG |
|---|---|---|
| I | 200 mg/m2 on day 1 | 120 mg/m2 i.v. bolus |
| Dose augmented from 25 mg/m2/day on day 2 to 5 | on day 1, 2 and 3 | |
| II | Dose augmented from 75 mg/m2/day on day 1 to 5 | 30 mg/m2/day i.v. |
| III | Dose augmented from 75 mg/m2/day on day 1 to 5 with pagfilgrastim between days 7 to 14 | infusion on days 1 to 5 |
