Table 4. Selected Clinical Diagnoses of Youths Treated With Antipsychotics With ADHDa.
| Selected Clinical Diagnosis | No. of Patients With ADHD | Youths Treated with Antipsychotics With ADHD, % (95% CI) | |||||
|---|---|---|---|---|---|---|---|
| Total (n = 4869) | Age, y | ||||||
| 3-5 (n = 432) | 6-12 (n = 1459) | 13-18 (n = 1832) | 19-24 (n = 1146) | ||||
| Any FDA-indicated or evidence-supported diagnosis | 19 990 | 52.7 (51.3-54.1) | 63.0 (58.4-67.5) | 58.5 (56.0-61.1) | 51.5 (49.2-53.8) | 43.3 (40.4-46.2) | |
| Any FDA-indicated diagnosisb | 35.1 (33.8-36.5) | 25.9 (21.8-30.1) | 30.4 (28.1-32.8) | 37.3 (35.1-39.6) | 41.1 (38.3-44.0) | ||
| Bipolar disorder | 2428 | 21.2 (20.0-22.3) | 6.3 (4.0-8.5) | 10.5 (8.9-12.1) | 26.5 (24.5-28.5) | 31.9 (29.2-34.6) | |
| Psychosis | 955 | 9.2 (8.4-10.0) | 0.9 (0-1.8) | 4.6 (3.5-5.7) | 11.6 (10.2-13.1) | 14.3 (12.3-16.3) | |
| Autism spectrum disorder | 3590 | 8.9 (8.1-9.7) | 19.0 (15.3-22.7) | 15.7 (13.8-17.6) | 5.2 (4.2-6.3) | 2.3 (1.4-3.1) | |
| Tourette disorder | 1568 | 2.2 (1.8-2.6) | 2.1 (0.7-3.4) | 3.6 (2.6-4.5) | 1.8 (1.2-2.4) | 1.0 (0.4-1.5) | |
| Any evidence-supported diagnosisb,c | 26.9 (25.6-28.1) | 50.7 (46.0-55.4) | 40.0 (37.5-42.5) | 24.4 (22.4-26.4) | 5.2 (3.9-6.4) | ||
| Oppositional defiant disorder | 6374 | 16.1 (15.1-17.2) | 28.7 (24.4-33.0) | 25.9 (23.7-28.2) | 15.0 (13.4-16.7) | 0.8 (0.3-1.3) | |
| Conduct disorder | 8414 | 16.1 (15.1-17.1) | 33.6 (29.1-38.0) | 22.0 (19.9-24.1) | 14.6 (13.0-16.2) | 4.5 (3.3-5.6) | |
Abbreviations: ADHD, attention-deficit/hyperactivity disorder; FDA, US Food and Drug Administration.
a
2010-2015 MarketScan Data.
b
Groups are not exclusive.
c
Includes pre-ADHD diagnosis study period and study year.