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. 2019 Jul 29;17:61. doi: 10.1186/s12958-019-0502-y

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Cd treatment disrupted physiologic functions of ovary. a Body weight were conducted every other day during Cd treatment, Cd (5 mg/kg) group are significantly lighter than the other groups from the fourth day of treatment. b Comparison of relative ovary weights between the groups. c Ovarian morphology by H&E staining. CL, corpus luteum; white arrow, antral follicle; yellow arrow, atretic follicle. The scale bars represent 250 μm (upper panel), 100 μm (lower panel). d Number of ovulated oocytes obtained from oviduct. Data are presented as means ± SD. *P < 0.05 and **P < 0.01, compared with the controls