Table 5.

Predictors of response to device therapy.

Author	Inclusion criteria	n	Study design	Predictors of response
Kotzampassi and colleagues125	Adults, BMI < 35 kg/m2 with comorbidities; BMI ⩾ 35 kg/m2 resistant to LMT for 6 months; or BMI ⩾ 50 kg/m2, receiving 6-month intragastric balloon	583	Retrospective analysis comparing successful (%EWL ⩾50%) and poor (%EWL <20%) responders	Older age, females, higher education level, single/divorced participants, and strict exercise commitment predicted success
Madeira and colleagues126	Adults, BMI ⩾ 30 kg/m2 and metabolic syndrome without DM, receiving 6- months intragastric balloon	50	Prospective 6-month study assessing predictors of weight loss response	Baseline advanced age and higher social relationship score associated with weight loss >10% at 6 months; weight loss >5% at 2 and 4 weeks and higher intensity of dyspepsia at 2 weeks predicted weight loss >10% at 6 months
Vargas and colleagues127	Adults, BMI > 30 kg/m2, receiving intragastric balloon	321	Retrospective analysis assessing safety, efficacy, and factors associated with intolerance and response to intragastric balloon	Greater number of follow-up visits and weight loss at 3 months associated with increased weight loss at 6 months

BMI, body mass index; DM, diabetes mellitus; EWL, excess weight loss; LMT, lifestyle modification therapy.