Table 1.

Inhibitory activities and binding energies of docked 2-phenoxypyrido[3,2-e][1,2,4]triazolo[1,5-a]pyrimidine derivatives and acarbose into the active site of α-glucosidase

Name of synthesized derivatives	Free binding energy (kcal/mol)	Number of hydrogen bonds	Number of closest residues
2a	− 8.12	1	10
3	− 9.17	3	6
6a	− 9.76	1	7
6b	− 9.42	3	9
6d	− 9.64	3	8
6h	− 10.55	3	7
Acarbose	− 10.56	10	10