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. 2018 Dec 11;25(1):22–33. doi: 10.1177/1753425918817611

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© The Author(s) 2018

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — OLFM4 is expressed solely in neutrophils. (a) qPCR of bone marrow cells showing OLFM4 is expressed exclusively in neutrophils, P = 0.008. (b) qPCR showing increased expression of OLFM4 6 h following LPS stimulation P = 0.006. (c) Histogram of bone marrow lineage depleted cells looking at c-Kit and Gr1, demonstrating maturation of neutrophils starting from 1 (immature) to 4 (mature neutrophil).³⁰ (d) qPCR from sorted populations of maturing neutrophils showing immature gene Mpo present only in population 1 and the mature neutrophil gene Mmp9 only expressed in population 4. Olfm4 expression can be detected in population 2 and increasing transcript in 3 and 4.