Table 9.
Relations of Arterial Stiffness to Composite Outcome of CVD Incidence or Death
| Arterial Stiffness Measure | Model Adjusted for Covariates But Not TOD | Model Adjusted for Covariates+Presence of TOD (Yes/No) | ||
|---|---|---|---|---|
| HR (95% CI) | P Value | HR (95% CI) | P Value | |
| CPP | 1.20 (1.10–1.30) | <0.0001 | 1.18 (1.09–1.29) | 0.0001 |
| % Attenuation upon adjustment for TOD | Referent | 6.2% | ||
| Central MAP | 1.05 (0.96–1.16) | 0.30 | 1.04 (0.94–1.15) | 0.45 |
| CFPWV | 1.09 (0.94–1.27) | 0.24 | 1.08 (0.93–1.25) | 0.31 |
| No. of events/No. at risk | 501/5803 | |||
Hazard ratios (HRs) are per 1‐SD increment in arterial stiffness measure and are adjusted for age, sex, body mass index, diabetes mellitus, antihypertensive treatment, smoking, total cholesterol/high‐density lipoprotein cholesterol ratio, triglycerides, lipid‐lowering medications, heart rate, and estimated glomerular filtration rate. CFPWV indicates carotid‐femoral pulse wave velocity; CPP, central pulse pressure; CVD, cardiovascular disease; MAP, mean arterial pressure; TOD, target organ damage.