Table S4.
All-cause and respiratory hospitalization by GOLD 2011 and GOLD 2017 classifications, univariate and multivariate* Cox proportional hazards regression analyses
| All-cause hospitalizations | Respiratory hospitalizations | |||
|---|---|---|---|---|
| GOLD group | Hazard ratio (95% CI) | Adjusted hazard ratio (95% CI) | Hazard ratio (95% CI) | Adjusted hazard ratio (95% CI) |
| 2011 group A | 1 | 1 | 1 | 1 |
| 2011 group B | 1.8 (1.3–2.3) | 1.6 (1.2–2.1) | 1.9 (0.8–4.5) | 2.0 (0.8–5.2) |
| 2011 group C | 1.7 (1.1–2.6) | 1.6 (1.0–2.4) | 2.7 (0.9–8.5) | 2.6 (0.8–8.4) |
| 2011 group D | 2.4 (1.8–3.1) | 2.0 (1.5–2.6) | 9.1 (4.2–19.6) | 9.6 (4.1–22.1) |
| Harrell’s C** | 0.60 | 0.66 | 0.72 | 0.77 |
| 2017 group A | 1 | 1 | 1 | 1 |
| 2017 group B | 1.9 (1.5–2.4) | 1.6 (1.3–2.1) | 5.8 (2.9–11.6) | 5.6 (2.7–11.6) |
| 2017 group C | 2.7 (1.5–4.7) | 3.5 (2.0–6.3) | 5.7 (1.5–21.0) | 8.1 (2.1–30.8) |
| 2017 group D | 3.0 (2.2–4.0) | 2.6 (1.9–3.5) | 12.1 (5.7–25.4) | 11.9 (5.4–26.2) |
| Harrell’s C** | 0.61 | 0.67 | 0.69 | 0.78 |
| 2017 group 2A | 1 | 1 | 1 | 1 |
| 2017 group 2B | 1.7 (1.3–2.3) | 1.5 (1.2–2.0) | 2.1 (0.8–5.3) | 2.2 (0.8–5.8) |
| 2017 group 2D | 3.2 (2.0–4.9) | 2.3 (1.5–3.7) | 9.4 (3.3–26.7) | 7.7 (2.6–23.3) |
| 2017 group 3B | 2.0 (1.5–2.8) | 1.7 (1.2–2.3) | 9.9 (4.4–22.3) | 8.3 (3.4–20.0) |
| 2017 group 3D | 2.4 (1.6–3.6) | 2.1 (1.3–3.2) | 12.4 (5.0–30.7) | 13.2 (5.0–34.8) |
| 2017 group 4B | 2.7 (1.8–4.0) | 2.2 (1.5–3.3 | 19.7 (8.5–45.7) | 20.3 (8.1–50.7) |
| 2017 group 4D | 5.1 (3.1–8.3) | 5.5 (3.3–9.1 | 26.6 (10.1–70.3) | 36.5 (12.7–104.5) |
| Harrell’s C** | 0.62 | 0.68 | 0.77 | 0.83 |
Notes: *Multivariate models adjusted for gender, age, smoking, body mass index, comorbidities (diabetes, angina/heart attack, high blood pressure). **Posthoc estimation of Harrel's C concordance statistic following Cox regression.